 If you liked
Kodomo no Omocha (TV)
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 ...then you might like
Hunter x Hunter (2011)
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Both are animes that look for kids, with childrens as main characters and a kawaii animation and artstyle, but as the story goes on gets more serious.
And Sana has similar personality with Gon, and they both have absent parents, aparently "dead" but they appair later on series.
Akito was abused by his family as Killua, and he was having a bad behavior (Killua being an assasin and Akito bullying his classmates and teachers) until they meet another character who helps him (Gon and Sana).
Also Killua friendship with Gon reminds me of Sana and Naozumi.
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Recommended by AtaruMoroboshiXD